Subcutaneous EEG – Forecasting of Epileptic Seizures (SUBER) ClinicalTrials.gov Identifier: NCT04061707 Sponsor: King’s College London Funding Institution: Epilepsy Foundation Subcutaneous EEG – Forecasting of Epileptic Seizures (SUBER) is a 1-year observational study (n=10), where patients with refractory focal epilepsy will undergo ultra-longterm continuous recording of subcutaneous EEG (implanted under local anesthesia) and non-invasive wrist-worn sensor bio-signals. Our
The UNFOLD study aims to identify the processes involved in developing an identity as a ‘person in recovery’, and how recovery from mental ill-health may ‘unfold’ over time. It is funded by the NIHR Biomedical Research Centre. To date, almost all empirical studies of recovery have been retrospective and focussed on psychological change. In this
ADHD Remote Technology (ART) Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that persists into adulthood in a significant proportion of individuals clinically diagnosed in childhood. The prevalence of ADHD among adults is 3-4% worldwide. The disorder is diagnosed based on impairing levels of inattentive, hyperactive and impulsive behaviours, but most adults with ADHD present
DynaMORE aims to promote stress resilience and improve mental health and well-being in the face of adversity. A joint goal of developing an in silico model of stress resilience. To do so, we monitor healthy at-risk individuals (18+ years old) during stressful life phases, such as transition into adulthood or higher education, training-to-street transition (police officers),
Health on the Move (HOME) Study: Using a smartphone app to explore the health of migrants in the United Kingdom Background In 2018, 14% of the people living in the UK were born abroad, yet we have a limited understanding of their health needs and broader determinants of health. To fill this knowledge gap, the
The RADAR programme aims to test if new pre-emptive therapeutic development and clinical care strategies based on remote continuous monitoring are both scientifically feasible and also practically feasible as part of a wider healthcare system. Early stages of Alzheimer’s Disease (AD) are associated with cognitive decline, overlapping with increasing functional decline (impairments in the ability
RATE-AF is an National Institute for Health Research (NIHR) funded study designed to compare two strategies of rate-control, based either on initial treatment with digoxin or beta-blockers in 160 patients with Atrial fibrillation (AF) in need for rate-control therapy. Monitoring with wearable devices, phone sensors and questionnaires will be conducted over a continuous 6 month
Multiple sclerosis (MS) is a condition in which the body’s immune system has an abnormal reaction to the central nervous system (CNS, made up of the brain, spinal cord and optic nerves). The immune system attacks elements of the CNS, disrupting the transmission of nerve signals and producing the symptoms that characterise MS. The exact
The MDD study is focused on the remote data collection aspect, since the study participants are not monitored in a hospital setting, but the data is collected passively in an real life assessment. Besides the sensor data from smartphones and wearables devices, participants actively report mood at random time points in daily life, using the
The epilepsy studies are running in University hospitals in the UK and in Germany. Goal of those pilot studies is the evaluation of wearable device data for passive remote monitoring of patients in an hospital epilepsy monitoring unit (EMU). The RADAR-base Android application, captures sensor data from consumer grade and medical grade wearables devices via
